Originally Posted by TenaciousB

To second what 11atsomto said, hub to hub commutes to or from DEN are difficult due to lots of positive space training travel and last minute listings. I did the commute SFO-DEN and it was not fun, but I made it work. If you can't get LAX I would suggest ORD given the fact that there will be more flights on other carriers as options compared to the other bases. And on United there are often WB aircraft DEN-ORD which increases the chances of seats in my experience (i.e. there tends to be at least a few no-shows or misconnects given the large numbers).

Also, don't commute to EWR... you're welcome.