I don't see why you wouldn't want to leave a regional as quickly as possible. Not all regional pilots came on board with 300 hours and a cfii(ok mei too). Some of us flew our #@!es off 135 and actually learned how to HAND FLY AIRPLANES without the autopilot(and aren't scared of weather) In my case, I have more tt and PIC turbine than MOST captains that I fly with, just need the 121 time.