Intentionally planning on a regional career is not a good idea for most folks. You need to go in with the intention of getting a major job. The real question you need to ask yourself: If you DON'T get a major job will you be willing to live with the consequences...
a) Stay at the regional, with low pay and lower stability.
b) Career change in your thirties.
A regional career might be suitable for a some people...
- Bohemian fun hogs who have NO intention of ever getting married or having kids. Most of these folks do too many drugs to qualify for 121.
- Small town folks who want a professional job but also want to keep the family farm.
- Folks who have a domicile in their home town...a good deal while it lasts, but most of these folks will quit if they get forced into a commute.
- People with money or a lucrative side job who can afford to not get paid a professional wage.
Try to search for other threads on this subject, there has been plenty of discussion.