Concur with the above....I went to it from a 56k lb. turboprop (E-2)..
For me,
- Taxiing was/is hardest! Fine line between keeping it rolling and rolling too fast.
- Getting the be-otch to slow down/come down. The late descent in ANC sucks, especially on the classic where you get speed brakes or flaps, not both. The key I've found is to be judicious use of the landing gear to add drag.
- Inertia: one of the instructors referred to the 747 as a fat woman: plan early where you want her to go, and don't let her get going to fast in any direction.

Beyond that, and overall, I found it way easier than the Hawkeye. Doesn't have any bad habits if you plan appropriately and it's actually nice to hand fly.

Spongebob