You're more likely to encounter Malaria in sub-Saharan Africa. I got it once and ended up getting hospitalized. I was on a common prophylaxis known as Lariam. It's side effects include hair loss, anxiety and nightmares after pro-longed use (I took it for a year). In order for those kinds of drugs to be affective, you usually have to start taking it a couple weeks before you go. If you're only going to be there for an over-night you're best off just wearing long sleeve shirts, Deat or just staying in doors. Random note: you can tell if a female mosquito is carrying the malaria virus if their back legs are sticking straight up in the air... no joke!