As you said, your married, probably don't want to stress the family with moving around the country time and time again for different jobs in different places. Regionals (as you know) have historically been stepping stones. If you go to a regional with the thought of it being a possible "career" airline, then you'll probably be able to enjoy the "fruits" of your flying career with a decent schedule, and moderate pay. Quick upgrades are only really important for getting out, or making some $$ in the meantime.

The regionals with better reputations will most likely yield you the better QOL. Look for Expressjet, and Skywest. On the contrary, i know it wasn't what you wanted, but, living in base can make a heck of a difference as well. An individual at a lower tier regional who lives in domicile, might experience a better QOL that an individual at a upper tier regional who commutes. I wouldn't go moving for the sake of commuting, but if there's something available around you, it might be worth considering.