I have been considering taking a break from flying for 2-5 years until things are a little more upbeat again so that I can pursue other endeavors. I am curious to get some opinions on just how difficult it would be to land a corporate or major job after taking a few years break?

Please assume:
1) the economy has rebounded and airlines are hiring once again with some growth and
2) pilot has ATP, 1300 PIC Turbine, 4000 TT, 737 and CL-65 Types.

What steps, if any, do you think would be necessary to have a major consider you and call you in for an interview?

Thanks!