Commuting from Germany to reserve at a US regional?! You sir, will be the picture of misery.

Most companies that I know of only give reserves 10-12 days off a month. Depending on the company only some of those days will be "hard" days off (unmovable by the company). Depending on whats going on that month, you can count on days off getting rolled/shifted based on company need. Or, if things are slow and your company doesn't have much flying that needs covering, you fly in from Germany and sit in a crashpad for 5 days then have 2 off (making it impossible to commute home) and then sit in the crashpad for another 5 days. Sounds miserable to me anyway you slice it. Assuming you like your family, I imagine it'll take you a month, maybe 2 of that hell before you pack up the family and move to the States.