All 121 training programs are approved by the FAA. There are certain items that they must hit regardless. Having been through two regionals and familiar with a major, they've been very similar.

However, even when you get into the same airline they might have different training programs. There was a very good thread in the cargo forum about UPS and the differences in programs there. Depending on the aircraft type, and who's running the program they can be very different even when under the same airline.

Regardless of who's operating the aircraft accidents still happen. Q-400s operated by Continental would not have prevented this because pilots with the same level of experience with the same standard of training (FAA approved) would have been operating the aircraft.