There is a similar thread in the 'leaving the career' section. I wanted out after about 8 total years in the 121 world. After being furloughed after 9/11, I found a normal job. Did that for a while and when things picked up, I was recalled, and went back into the fray. It didn't take long for me to regret going back. I realized I wanted out for good. Well, I got lucky and a position opened up at my old non flying job.
I was once again living life. Much better pay, living in my hometown again, home every night, holidays off and at home, better benefits (pension!), liberal time off (4 day work week and oodles of vacation, comp, and personal time), etc. So far the economy resulted in a whopping 1% paycut, but balanced by an additional 4 days off per yr. to compensate. Oh, and an office job it's not.
The only things I miss are seeing the different cities, some of the people, and hand flying the plane. Otherwise life is great, better then it has ever been for me. I just wish I could get back all the time and money I dumped into flying.