Look long term- do you like the 91 atmosphere? Do you live in a "hub" city? Find guys who fly for companies you may be interested and pick their brains. There is no "yes/no" to your question. It all boils down to where you are, where you want your career to end up, and what are your priorities in life. Need a fixed schedule- airlines can give you that, but so can some 91/fractionals. Don't want to move? Well some fractionals have home basing, airlines is commuting. Job security- both have risk. Look at majors, look at regionals, look at fractionals, and call up some corporate departments. Is not about where you are- it's where you want to be in your career when it's all said and done. There is no "easy street" in this industry (unless your hooked up to a fortune 50 company from the get-go)