Select at random, one of the popular anti malaria medications, and read the package insert with all the warnings and cautions. Pretty scary stuff. Most are intended for very short term use (weeks, not months) Air France, which does a lot of bid-ness there has lost several crewmembers to malaria in recent history.
Full disclosure: I've spent a good bit of time on the African continent in the past year. It's ok in small doses, as long as you are fully aware of what you are getting into. Africa (anywhere North of Jo'berg) is NOT a place to be taken lightly.
Fly Safe out there