An important thing to consider is where your wife ends up. You'll have to work around her job situation. Depending on where it is, you might not be too happy with a regional that doesn't have a base in your city. In fact, you might want to ONLY consider a job that has a base in your city. I'd say 3 to 5 years to 50K if you go regionals, depending on which one. Corporate or a good 135 outfit will pay you that eventually. Heck, with you wife's income you could buy a nice plane to instruct out of and maybe do alright freelancing. You'd have to love instructing, though, and develop a high end clientel.
I just think, if you're not the ultimate breadwinner in the family, you're not gonna want to go out and do the usual "commute to a regional job" lifestyle.