I know in my time in it, the heavier you are, the more momentum you'll need to get up into the flight levels. Above 24,000 lbs, I will do a 190 to 200 knot climb. That'll get you a good climb rate and plenty of energy up to about 18 or 20,000 feet. Above that, 180 knots works for a while until 500 fpm, then finish out the climb at 500 fpm. Below 24000 lbs, 180 knots works fine all the way up to 22 to 23,000 feet, then gradually bleeds off.

If it's cold, airplane very happy. When it's warm, airplane not so happy. When it's warm, the 190 to 200 kt climb works well.