MC,
I am a SWA guy and my best bud down the road is a FedEx guy. I've been here for 5 years and he's been there for 9. Neither of us have ever complained about our respective QOL both with 2 kids each. He's on the MD11 and I'm on the 737

Obviously schedules are different, but I think we both get comparable time off. Their vacation is better. Other than that, I'm pretty convinced our time at home is about the same.
-fate