It's noticeably less reliable than the Airbus, at least in JetBlue's fleet. Overall dispatch rate varies, sometimes nearly the same and sometimes 1-2 percentage points lower. I haven't personally had a jet be completely unflyable in 3 years here (other than an air turn-back for hydraulic failure), but the percentage of nuisance faults and glitches that cause delays and headaches is plenty high.
I like the jet well enough when it works, and customers generally rave about it (except when the Tvs break, which is also at a higher rate than Fifi). I just wish Embraer had done a better job engineering the thing, and whoever designed the seats should be shot.