If you go into your room in the layover hotel and find the telltale signs described, why don't you march back down to the reception and demand another room?

Does your airline's Hotel Committee know about this?

Are bed bugs found on airplane seats as well?

When staying in hotels, I'm sometimes more afraid of the cooties in the bathroom, on the remote control, on the curtains, telephone. Also afraid of viruses, mold and fungus. Making myself sick here.