Dave: From what I have heard at FedEx, recency of experience isn't as big a factor as it is at other airlines. That may be partly because they figure you are going into the back seat for at least a year, but who knows. I met several pilots here who hadn't flown for several years when they got hired here. Having access to a sim would be most helpful prior to the interview, and as long as you can get through the sim eval during the interview I don't think recency is a big issue here.
Good luck.