Carl offers some good advice. Things are going to get dicey again in my opinion. UAL has announced they may be grounding 44 aircraft (737-500 & 767-200ER) very soon due to the increased hit on the balance sheet caused by fuel prices. They likely will not be the only ones, so keep that in mind when you are looking.

If you still want to make the move, consider a place like Atlas. 747-400/8F cargo flying all around the world. They are also now doing passenger ops and look like they will be adding 767's very soon. The company is very strong financially, the pilots have a new contract with good pay raises and they just announced that the profit charing checks will be 20.1% of base pay and overtime for last year. For even a junior F/O, that's a huge chunk of change.

They are hiring and will be doing so for quite awhile. 14 747-8's are in the pipeline with options on 12 more. They will lose a fair number of folks to age 65 in the coming months. If you don't mind the travel and like flying a nice plane, it's a darn good gig.

And given the way that their management has run the company since they exited bankruptcy in 2005, which has been very solid, they are much less likely to end up in the recall/furlough cycle that others do.