Seeing as how I fly for an airline that does several of these routes ... I can say that some of them are worth it, while others' aren't. I can't count the number of times I've flown to VCT, PQI, PKB, AOO, SHD, etc. with 2-3 pax on just one leg. Pretty sure I've done it w/o any pax a number of times as well. Most of these cities are a solid 2 hr drive (there are some exceptions to this of course) from any city with scheduled air service .. so it would be a pain to make that drive when you need to go somewhere ... but at the same time how often do people that live there actually have to travel??