Airline Pilot Central Forums

Airline Pilot Central Forums (https://www.airlinepilotforums.com/)
-   COVID19 (https://www.airlinepilotforums.com/covid19/)
-   -   Vaccine Development Summary (https://www.airlinepilotforums.com/covid19/130375-vaccine-development-summary.html)

Flyfalcons 11-27-2020 09:06 AM


Originally Posted by GateAgent007 (Post 3163893)
If the vaccine fails, then yes, you can still get COVID. There is nothing wrong with that speculative statement. If it bothers you so much, go get an antibody test after your vaccinations. If the vaccine is effective and you have antibodies, then you can go take off your mask.

Good lord, the whining is non-stop.

Edit: This vaccine may provide full immunity like the polio or rubella vaccine, but it also might only provide partial immunity, like the influenza vaccine. In the second case, you can still catch the Coronavirus. It just won't put you in the hospital anymore. If that is the case, then we'd have to wear masks until all the high-risk individuals were immunized. Which is why they're the priority below essential medical personnel.

Time will tell.

No whining here, just explaining the fact that you can be vaccinated and still spread the virus. You're the one with the problem here. Arguing against what the experts are saying just so you can feel right (and running multiple user names here) says more about your mental instability than my accuracy.

rickair7777 11-27-2020 09:55 AM

Pharma group expects ten viable vaccines by mid-2021.

Some debate over intellectual property and compulsory licensing.

https://www.reuters.com/article/heal...-idUSKBN2871UV

rickair7777 11-27-2020 09:58 AM

Blowback over AZ's messaging on efficacy...

https://www.reuters.com/article/us-h...-idUSKBN28714L

Excargodog 11-27-2020 10:38 AM


Originally Posted by rickair7777 (Post 3163933)
Blowback over AZ's messaging on efficacy...

https://www.reuters.com/article/us-h...-idUSKBN28714L

Touting 90% efficacy when the stats showed 63% will attract attention, SEC attention if a single insider sold any shares during the subsequent price bump.

rickair7777 11-27-2020 10:50 AM


Originally Posted by Excargodog (Post 3163954)
Touting 90% efficacy when the stats showed 63% will attract attention, SEC attention if a single insider sold any shares during the subsequent price bump.

Maybe. They did legitimately have a subset of the data that showed 90%, probably enough reasonable doubt to stay out of jail.

rickair7777 11-28-2020 02:10 PM

Indian vaccine producer endorses AZ vaccine trial results, plans to seek approval in India. States no cases severe enough for hospitalization. Also states those trial participant who did get covid were not infectious to others (not sure how they assessed that).


https://www.reuters.com/article/us-h...-idUSKBN2880H9

BoilerUP 11-30-2020 05:03 AM

Moderna to request COVID vaccine EUA from FDA today; revised Phase 3 trial data shows 94.1% efficacy.

Pfizer's EUA application will be reviewed 10 Dec, Moderna's EUA application one week later on 17 Dec.

rickair7777 11-30-2020 06:39 AM

Another article about Moderna. Official trial data confirms 94% efficacy, and 100% efficacy against severe cases.

https://www.reuters.com/article/us-h...-idUSKBN28A1IU

Excargodog 11-30-2020 08:08 AM


Originally Posted by rickair7777 (Post 3164815)
Another article about Moderna. Official trial data confirms 94% efficacy, and 100% efficacy against severe cases.

https://www.reuters.com/article/us-h...-idUSKBN28A1IU


if they’ve got anything like 94% efficacy for prevention they have WAY TOO FEW actual cases - at least this early - among the immunized to go touting “100% efficacy against severe cases.” They only HAD 11 cases among the immunized and the statistical expectation is that even if these were all in 65+ age group you would have only had about one serious case.

At best they can say “we haven’t had a single severe case among the immunized so far.” The confidence interval would be WAY TOO broad to say 100%. Expecting one and getting none is not a statistically unlikely event in this context.


The company said 185 cases of Covid were observed in the placebo group versus 11 cases observed in the group that received its vaccine.
Not saying it isn’t good news though, just that getting to 100% of anything in population statistics is tough.

rickair7777 11-30-2020 08:34 AM


Originally Posted by Excargodog (Post 3164842)
if they’ve got anything like 94% efficacy for prevention they have WAY TOO FEW actual cases - at least this early - among the immunized to go touting “100% efficacy against severe cases.” They only HAD 11 cases among the immunized and the statistical expectation is that even if these were all in 65+ age group you would have only had about one serious case.

At best they can say “we haven’t had a single severe case among the immunized so far.” The confidence interval would be WAY TOO broad to say 100%. Expecting one and getting none is not a statistically unlikely event in this context.



Not saying it isn’t good news though, just that getting to 100% of anything in population statistics is tough.

They know what they're doing, statistically speaking. The trail result was 100% prevention of severe cases.

IIRC in statistics extreme results are much more likely to have a tight margin of error, than middle of the road results.

Also your "11 cases" logic is a complete falacy... what they ACTUALLY had was 15,000 vaccine recipients, NONE of who got severe covid. For the severe covid metric it's statistically irrelevant how many got mild covid. I'm assuming but don't know that the study group was split 50/50 between vaccine and placebo, if not I'm sure it was fairly close.


All times are GMT -8. The time now is 12:54 AM.


User Alert System provided by Advanced User Tagging v3.3.0 (Lite) - vBulletin Mods & Addons Copyright © 2024 DragonByte Technologies Ltd.
Website Copyright ©2000 - 2017 MH Sub I, LLC dba Internet Brands