mRNA Vaccines
11-16-2020, 08:35 AM
#11
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Originally Posted by Mesabah
I'm still going with the AstraZeneca vaccine, never go with the A model of anything.
If I had to choose, my limited (but better than layman) professional knowledge in biotech leads me to prefer the mRNA. Very specific, very targeted. Kind of like would you rather your family fly in an A220 or a Ford Tri-motor? A220 has lots of modern tech, but is relatively new and you could make the case unproven. The Tri-motor must be much safer though because it has almost 100 years of operational experience.
But I'll take whichever is first available, unless I need a specific vaccine to clear customs or there's significant known differences in efficacy.
11-16-2020, 08:40 AM
#12
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I hear Dr. Alice Krippin is the leading researcher on the vaccine, which is great news.
https://m.youtube.com/watch?v=B3xY6Ffy_wE
https://m.youtube.com/watch?v=B3xY6Ffy_wE
11-16-2020, 08:50 AM
#13
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Posts: 399
Originally Posted by da42pilot
Apparently the Pfizer vaccine has a stronger immune reaction. I wonder if they’ll prioritize Pfizer to the elderly given that they have more trouble getting an immune response.
11-16-2020, 11:54 AM
#14
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Originally Posted by rickair7777
If I had to choose, my limited (but better than layman) professional knowledge in biotech leads me to prefer the mRNA. Very specific, very targeted. Kind of like would you rather your family fly in an A220 or a Ford Tri-motor? A220 has lots of modern tech, but is relatively new and you could make the case unproven. The Tri-motor must be much safer though because it has almost 100 years of operational experience.
But I'll take whichever is first available, unless I need a specific vaccine to clear customs or there's significant known differences in efficacy.
But I'll take whichever is first available, unless I need a specific vaccine to clear customs or there's significant known differences in efficacy.
11-16-2020, 12:09 PM
#15
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Originally Posted by Speed Select
I hear Dr. Alice Krippin is the leading researcher on the vaccine, which is great news.
https://m.youtube.com/watch?v=B3xY6Ffy_wE
https://m.youtube.com/watch?v=B3xY6Ffy_wE
11-16-2020, 02:17 PM
#16
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Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,293
Originally Posted by Mesabah
I don't think that is an accurate analogy, the type of vaccine that the AZ one is, has been given to me before, and my body tolerated it very well.
A viral vector covid vaccine might not (likely not) use the same vector as a vaccine you already had. If it is the same vector, your system might actually have acquired immunity to that vector... making you immune to your covid vaccine!
I like mRNA because it's precise. Viral vectors are potentially sloppy, somewhat more of a blunt instrument.
mRNA is new, some folks are more comfortable with new than others.
11-17-2020, 07:12 AM
#17
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Originally Posted by Speed Select
I hear Dr. Alice Krippin is the leading researcher on the vaccine, which is great news.
https://m.youtube.com/watch?v=B3xY6Ffy_wE
https://m.youtube.com/watch?v=B3xY6Ffy_wE
11-22-2020, 02:09 PM
#19
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Posts: 11,504
Originally Posted by Speed Select
I hear Dr. Alice Krippin is the leading researcher on the vaccine, which is great news.
https://m.youtube.com/watch?v=B3xY6Ffy_wE
https://m.youtube.com/watch?v=B3xY6Ffy_wE
That actually was well played.
it is very possible that mRNA vaccines are going to be like a combination of CAD and 3D printers, giving fast prototyping and speedy output. But Mesabah does have a point about A models. There was nothing all that cosmic about the technology of the Salk vaccine inactivating live polio with formaldehyde, but Cutter labs still managed to FUBAR a batch.
In April 1955 more than 200 000 children in five Western and mid-Western USA states received a polio vaccine in which the process of inactivating the live virus proved to be defective. Within days there were reports of paralysis and within a month the first mass vaccination programme against polio had to be abandoned. Subsequent investigations revealed that the vaccine, manufactured by the California-based family firm of Cutter Laboratories, had caused 40 000 cases of polio, leaving 200 children with varying degrees of paralysis and killing 10.
There are old pilots and bold pilots...
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