With 250 ME (assuming that it's actual legit ME... that number with 600TT raises a flag right off), he should be marketable to most of the regionals out there (regardless of their published minimums).

I'd suggest that he send a resume out to any regional airline that he's interested in, and see who nibbles. Remember that posted minimums are there as guidelines and also to weed out a lot of the chaff. Just because you don't make all the minimums doesn't mean you won't be offered an interview (IE if you have either a lot of TT or ME, but are short in other categories).