This is counter-intuitive. Almost nobody goes to the regionals because they would rather be there than a major. It's a stepping stone, and hard to avoid.

Your most realistic option to avoid regionals would be look into military flying opportunities.

You might also get lucky due to timing...if a serious pilot shortage develops in 5-10 years, majors might be hiring anyone with 1500 hours and turbine time. But I wouldn't plan my career around the "pilot shortage"