Mesa Airlines Pilot Development (MAPD) is a set curriculum that starts you from zero and goes to Commercial/Multi-engine/Instrument ratings plus some jet (CRJ) groundschool and sim training. The program is run out of San Juan College in Farmington, NM, at ASU, and some other school in the midwest. San Juan is a 2 year program with an AA degree, I think ASU is a 4 year BS.

There are many other similar programs out there, some of which will actually get you an interview with a regional/commuter airline, but MAPD does have a very high success rate for getting people hired at Mesa, like 80%.

My usual recomendation is to get your instructor ratings and teach, then you will be competetive for more than one airline. If you chose MAPD, I will say that it is a good program that does what it claims (rare in the flight training industry!). HOWEVER, be aware that is costs a lot of $$$ and if you are in the wrong 20% or Mesa stops hiring, then you've blown that money. That training WILL NOT get you a job at any other airline. You would then need to go get your instructor ratings anyway. Basically it's a calculated risk...do you feel lucky?

Also, there is some sentiment in the industry that 300 hour airline pilots "didn't pay their dues" or "bought a job" and aren't real pilots. This could haunt you in the long run when you apply to a larger airline. I don't care about dues paying myself, but a FEW MAPD grads are just kids with no judgement or backbone who would have benefited from a few life experiences. Shouldn't apply in your case if you play college ball...

www.mesa-air.com has more info.