Thanks to all for the helpful replies. I do realize I would need to get my ATPMEL. Just wondered if my overall background (Navy pilots are trained as an instrument-rated airplane pilot first, then transition to helicopters), may warrant some consideration.

As for the regionals - if they are getting desperate enough, I wonder if they would consider employing a "part-time" pilot. My Part 135 helicopter schedule is 7 days on / 7 days off / 7 nights on / 7 days off, much like a NetJets schedule. I know the conventional wisdom would say "no", but I wonder if they may consider working within my current schedule for say, 6 days per month. Why do I even ask this question? Kids to feed, mortgage to pay, etc. That Regional FO pay is...well, you know...

Assuming this is not possible, and I did bite the bullet and fly regionals full time, I do wonder, if I got hired by the majors after a couple years in the regionals, how long of an upgrade time I could expect with all the changes in the industry? If it would be potentially 10+ years as an FO in the majors before making Captain in my mid-50's, it may not be worth it.

As for NetJets, it looks like they do have a hard-and-fast 500 hours Multiengine Airplane requirement. Good to know they consider helicopter time though (I would assume for the TT requirement)

Since I now live near a major airport (PHX), this is the time to consider making this change. Helicopters are fun but they just don't pay like airlines do long term. Unless you fly internationally and are away 6+ weeks at a time...