Originally Posted by FaceBiten

You won't need to worry about upgrade time IMO. You just need recency and you will likely be working at a major before you would upgrade anywhere. I would say once you get a couple hundred hours of 121 you will get hired by a major if your apps are updated. But, if upgrade time is really what you are after, psa/TSA are probably the best options. Mesa could announce a bunch of new flying and it will be the place to go. It's a crapshoot, gambling on a bunch of crap companies. Skywest has typically been the golden boy, but my friends over there say things are getting pretty bad there.
I would recommend going to a regional that has a base where you live or could easily commute. Mesa, despite all the bashing and infantile people who post on this board, generally has a good pilot group, and I havent been messed with too much by the company. Minus the pay, I am happy here. So if phx, IAH, dfw, or iad work for you, it's not a bad place to be. I'm still working to get a couple friends over here.