I don't understand going to another regional to start with. Do your homework then pick one you want to stay with then stay there. Why go to one you know you are going to hate? Just be a cfi or fly freight till you get what you want. Seniority is everything.

There were a couple TSA guys that were interviewed at RAH not very long ago. The chief pilot for CHQ came down on them pretty hard about abandoning their company. Said it showed something about their character and made them a higher liability to hire. I took a few new hires I saw at the hotel for XJT to lunch since I had a vehicle two days ago. He was one of them and was a nice and intelligent guy. They simply didn't like the fact that he hadn't shown loyalty.

Depending on how the person hiring you feels it could hurt.