The 88 is not that difficult. It does require more vigilance and focus. Monitor the FMA closely, make sure your input is correct and NEVER EVER get SLOW at altitude or on final.

Don't rely too much on the automation. Be ready to hand fly to correct crazy Vnav decents. Get the plane under control and reengage the automation.

The most difficult part of 88 flying is the schedule. 4-5 day trips, multiple legs daily, many O'dark thirty departures, hot cockpits and high traffic airport environments, all add up to fatigue.

Remember to take things slow and trust but verify the FMA.

Good luck!!!