Fact

As soon as you are done with Mission Qual in your manned airplane (assuming you didn't get RPAs in pilot training), you will start the downward spiral of flying less and less the older you get with more and more queep unrelated to the mission. You will become unproficient and your hours will barely crawl by. Mileage may vary depending on what you fly. You have little to zero input on where you are stationed and eventually will probably end up in a desert hotspot 365 working power points instead of flying.

With guard/reserves, after your seasoning tour and 750, you can get your ATP, get on with a regional and build hours fast and eventually get to a major. You also get to still serve your country/ deploy if you want to etc.

Make no mistake, active duty does not provide any special product that the guard/reserves do not provide to air power. The ground pounder you will probably support as a cargo guy could care less whether the pilots airdropping or offloading his supplies are active duty or guard/reserve, same could be said about the guys dropping bombs or providing ISR.

Now, if you don't have interest in flying for a career and want to climb the career ladder, active duty is your answer.