Nothing here we haven't all speculated about for years. Flying boxes has always been way more expensive than a ground option. In the age of "free" shipping, where nothing is or ever was "free", nobody likes paying for first class when economy is offered for free. Fedex, UPS and DHL need to continue to cultivate the market for expedited freight. It will always be a niche part of the delivery business and as a precent of shipping, will only grow smaller. Amazon's warehouses can't store everything possible thing that someone near by need/wants. Expensive and perishable medical supplies are but one product we will all be flighting to keep out of Amazon's clutches. Time will tell.