There isn't that much room below the pylons with High bypass engines getting larger and low wing tips on RJ's. Try a crosswind above about thirty knots with a 172. Not enough rudder to get the nose straight. Same applies for all aircraft, at some point the rudder will not overcome the cross wind.

I have attached a video of a 787 doing cross wind testing in Iceland. Notice that the plane never enters a slip. Crabs until close to the ground then kicks the nose straight and plants the aircraft. The ailerons and spoilers on the upwind wing don't come up until just as the plane touches down. Look how close the pylons are to the ground. If you tried to slip the aircraft in that wind those pylons would hit.

B787 Crosswind Testing in Iceland #Dreamliner - YouTube