As you note the market has changed substantially. Nobody has experience with current conditions so we’re all spitballing. That said

1) 1500 and a pulse used to have regionals fighting over you. It doesn’t get you anywhere now, and there’s no workaround. The regionals that are hiring FO’s know their power.

2) look outside 121. Part 91 turbine and 135 are your best options. Maybe cape air.

The majors are hungry enough for pilots that 1-2 years non-121 turbine experience will likely let you bypass the regionals