There is plenty of advise on other forums, Re: Fedex. To somerize, you need inside contacts who will sponser you, the more the merrier. They will know (or can find out) what is needed to get you in the door.
Now if you don't have inside help, there are two options that can help. 1) apply to the training department or corprate flight department. Either of these may work without the "inside" contact. 2) Less desireable but also a good bet, take a job working for Fedex (express not ground!) and apply as an internal. Keep in mind you must still meet Fedex's mins quals. And give your ground job either 1 or 2 years. Check http://pilot.fedex.com for info about current quals. Good luck!!