Flying narcotics or crossing a picket line would get you blacklisted.

At some airlines where pilots have a role in the interview process, pay-for-a-job programs (like GIA) may cause an interviewer/hiring board member to give you a thumbs down.

Other than that, different types of flight time only matter in that some make you more competitive than others...it's much better to have lower-quality time than no time at all!