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Originally Posted by Phins2right
(Post 3025905)
At this point, what difference does it make? The $4it works.
And Cuomo. And France. And India. And China. And South Korea. |
This was the 2005 Study on HCQ and Coronavirus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/ Background Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available. Results We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations. Conclusion Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds. |
Originally Posted by forgot to bid
(Post 3025940)
This was the 2005 Study on HCQ and Coronavirus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/ Good news there is before or after. Now before we raid Mesaba's house and take his stash... and whatever other stashes he has... and if he as mustache we'll take that too... I believe they're reserving this to when you get hospitalized since as many as 50% I believe are asymptomatic. You don't need it because your body is superior. |
Originally Posted by CBreezy
(Post 3025957)
I'm not saying it doesn't work. I'm saying the paper is fraudulent. According to the article, both Stanford and Alabama have said they did not do anything to contribute to the paper. It also isn't peer reviewed. Trump's right hand man, Dr Fauci, has cautioned that all the evidence so far is anecdotal and it isn't clear that it is helping. This is the guy Trump has standing next to him in pressers.
BTW is the information in the article incorrect? |
Another anecdote...
Opinion: What I learned running a Beaumont COVID-19 floor I completed four days as the attending physicianon a COVID-19 floor at my local hospital, and here is some of what I learned: First, this is like nothing we have seen before. This virus is its own animal — it’s totally different in so many ways. As a physician, so much of what I’ve learned to treat over the years does not apply. Throw conventional wisdom out the window. Thought we treated sepsis with fluids? Think again. Thought we treated chronic obstructive pulmonary disease exacerbations with steroids? Think again. Thought we ventilated people with pneumonia on their backs? Think again. Think we knew much about anything? A medical worker transports a patient at Montefiore Medical Center, Wednesday, April 1, 2020, in New York. The new coronavirus causes mild or moderate symptoms for most people, but for some, especially older adults and people with existing health problems, it can cause more severe illness or death. (Photo: Mary Altaffer, AP) I showed up ready to serve, like thousands of my colleagues and health care workers across the globe. This is totally different. Second, most in the health care profession don’t whine. They just do it. I’ve never seen anything like it before. Doctors, nurses, aids, clerks, janitorial staff: They show up every day. They are apolitical. They believe in humanity, however imperfect. Third, there is hope in all adversity. We have to listen for the truths buried within the struggle. It may be transformative. No one can do this for us. Fourth, I have some guarded hope for treatment. This virus is nasty. I’m the first to admit that I did not “get it.” Now I do. All of the practitioners on the front lines see how bad it can be. I won’t quote outcomes, but we’re gathering data as we go. There will be more studies published over the next few months than can be digested in a lifetime. I don’t claim to be any authority. Most of us only have observational, nonscientific analysis, but I had some positive results. Yes, I think I did. I ran a floor of COVID-19 positive patients with severe symptoms. Our team used the combo of hydroxychloroquine with azithromycin and it seemed to help! Of the patients that I treated for these four days who where acutely ill — all ages and health conditions — most (loosely defined and footnoted) seemed to improve and were able to be discharged home. I can say that I transferred no one to the ICU but I sent many people home. Progress? I sure hope so. Would they have responded without? I don’t know. Unfortunately, there are also very severe cases whose victims aren’t as fortunate. When people go bad, they go bad quickly. Please keep them in your prayers. None of us know why this is happening or where it will lead, but there is no better time to accept that we are all in this together. Let’s all listen and learn. God bless. Dr. Christopher R. DeAngelis is an internal medicine physician based in Woodhaven, on staff at Beaumont-Trenton. He lives in Grosse Ile. |
Originally Posted by forgot to bid
(Post 3025961)
The guy who also wants to maintain the lockdown until no more deaths and no more cases. How long will that take?
BTW is the information in the article incorrect? |
Originally Posted by BoilerUP
(Post 3025962)
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Breezy,
Just curious, Are you saying that if you or a loved one contracted COVID-19 and was in ICU, that you would refuse hydroxychloroquine and Z pac ? Edit....for someone who is “not saying that” it sure comes across that that is what you are saying. Very Debbie Downerish. I’m not touting false hope but most people think this is a positive direction and you seem to want to argue that it’s not. |
Its funny how we have near nationwide legalization and retail non Rx dispensing of a drug that arrived at such acceptance based almost entirely on anecdotal argument.
Propagated in large part by media and political interests. Yet in this case, facing a worst case of millions of deaths.....those same media and political interests are allied against a benign medication that has been in use for half a century. Of course this time there is no benefit of yet more tax revenue, or anesthesia effect on the publics consciousness. Which makes the media and political personalities claims of a financial windfall for supporters of the efficacy of this anti malarial drug incredibly hypocritical. |
Originally Posted by forgot to bid
(Post 3025937)
There are some that don't want there to be the medicine that helps.
A month ago this entire thing was hoax from the MSM. Then it was nothing worse then the seasonal flu. Then it was only deadly to old people. Then people thought we could "fast track" a vaccine. Then there were people thinking that we had herd immunity already. Then people started looking at China and South Korea thinking that since they were through the worst of it, then we would soon be too. Then people looked at Sweden and assumed we could do the same. Now there is a miracle drug hydroxychloroquine. I'm not saying it won't help, but it won't be enough to stop social distancing and prevent the economic downturn. Offering false hope isn't going to help anyone. If it is a magic bullet, then peer reviewed studies will indicate that in the coming months. And even if that is the case, there isn't enough supply to save us. |
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