Another delayed lockdown effect…
08-14-2021, 07:35 PM
#12
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Everybody loves a good butt joke, but it really is a life and death issue.
And that applies equally to mammograms, Pap smears…even childhood immunizations which got backlogged during the lockdowns.
Patients whose cancer was detected by screening colonoscopy or FOBT had substantially higher overall survival and CRC specific survival 5 years after diagnosis (>85% and >90%, respectively) than patients whose cancer was detected by symptoms or otherwise (<70% and <75%, respectively). After adjustment for age, sex and education, patients whose cancer was detected by screening colonoscopy had a 65% lower total mortality than patients with symptom-detected cancers (hazard ratio, HR, 0.35, 95% confidence interval, 95% CI, 0.24-0.50) (Table (Table3).3). A 50% mortality reduction persisted even after additional control for stage and location of the cancer (HR 0.50, 95% CI 0.34-0.73)
Results We analysed 1747 patients who died from colorectal cancer and 3460 colorectal cancer-free controls. Compared with no endoscopic screening, receipt of a screening colonoscopy was associated with a 67% reduction in the risk of death from any colorectal cancer (adjusted OR (aOR)=0.33, 95% CI 0.21 to 0.52). By cancer location, screening colonoscopy was associated with a 65% reduction in risk of death for right-colon cancers (aOR=0.35, CI 0.18 to 0.65) and a 75% reduction for left-colon/rectal cancers (aOR=0.25, CI 0.12 to 0.53).
Conclusions Screening colonoscopy was associated with a substantial and comparably decreased mortality risk for both right-sided and left-sided cancers within a large community-based population
Conclusions Screening colonoscopy was associated with a substantial and comparably decreased mortality risk for both right-sided and left-sided cancers within a large community-based population
08-15-2021, 06:23 AM
#14
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Joined APC: Jan 2006
Position: Engines Turn Or People Swim
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Originally Posted by Mesabah
Coming soon to Covid…
https://pubmed.ncbi.nlm.nih.gov/34384810/
https://pubmed.ncbi.nlm.nih.gov/34384810/
Like Boiler said, we'd have seen it by now.
08-15-2021, 11:47 AM
#15
Speed, Power, Accuracy
Joined APC: Sep 2007
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Originally Posted by rickair7777
"enhancing antibodies have a higher affinity for Delta variants" is not the same as "high enough to be a problem".
Like Boiler said, we'd have seen it by now.
Like Boiler said, we'd have seen it by now.
08-15-2021, 12:05 PM
#16
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Originally Posted by GeeWizDriver
You mean, like the case fatality rate in Britain is now HIGHER for fully vaccinated than unvaccinated?
By and large, COVID non naive people (vaccinated or infected and recovered) are going to handle an infection much better than their age matched naive comparisons, but having a degree of immunity to COVID don’t make anyone immortal…
08-15-2021, 01:20 PM
#18
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Originally Posted by GeeWizDriver
Perhaps. But given what is starting to happen in Israel, Britain, Iceland, and elsewhere, it seems to me ADE is real and is going to be a problem.
You can never say never, but at present there is no real evidence these immunizations are a problem with ADE and the risk lessens everyday that no problem is identified.
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