Airline Pilot Central Forums - Ethics of COVID immunization in kids

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Quote:

Originally Posted by Excargodog (Post 3293329)

Nor is anyone saying it is.

Yes they are because I read posts on here beating this dumb drum (no pun intended for the Delta folks) over and over again, this thread included.

Quote:

Originally Posted by rickair7777 (Post 3293152)

It was always well within the scope of reasonable reality that this thing would become endemic and require periodic vaccine updates. Just like the flu but most likely less often. Since previous vaccination will generally confer *some* longer-term immunity even across variants, it's unlikely that you'd need a full three-dose regimen each year... more likely an annual booster that's updated as required for any new variants.

https://www.newsnationnow.com/health...9-flu-vaccine/

The end game isn't stamping it out, it's finding the balance point where we can live with. Since it's more political than the flu, that balance point might be different than for the flu although eventually it should all settle out. At some point covid hysteria won't be fun and exciting any more.

The variants haven't actually escaped the antibodies, for example, Delta requires higher antibody levels for neutralization due to its greater binding ability. The antibodies basically work by unfolding the spike protein, not allowing ace2 site binding. Antibodies made for this are from the full antigen, locked in its prefusion form by a proline substitution mutation. The vaccine encodes the entire spike antigen to express via antigen presenting cells. This is a safety feature, otherwise you would get sub-optimal antibodies that enhance inflammation.

Every virus has an evolutionary trick to fool the immune system, Covid's trick is it blocks its spike antigen express to T-cells. This is devastating to the vaccine, as it can't confer long term immunity without antibody levels artificially stimulated above neutralization. If variants do finally escape neutralization from antibodies(Covid is on that evolutionary path, probably due to the vaccine schedule), then a completely new antigen is needed for the vaccine, requiring the primer/booster dose to achieve neutralization levels.

(The most effective vaccine, is the one with the highest dose, i.e. Moderna)

Quote:

Originally Posted by Mesabah (Post 3293414)

The Israeli studies continue to be chock full of interesting data and information.

For example, after reading several of the studies (easy to find online) they show us that the variants are mutations which randomly occur. They'll always be out there.

By putting a "leaky" selective pressure on that virus population, however, selects for the fitter viruses. And here we are...

Fascinating stuff really.

Quote:

Originally Posted by Drum (Post 3294122)

“fitter” doesn’t necessarily mean more lethal. In fact, there is pretty good evidence that many pathogens have become less lethal over time allowing infectious people to survive longer to infect other people. Cholera back in Elizabethan times was far more lethal than it is today. The El Tor mutation let people live longer and spread cholera longer.

https://journals.asm.org/doi/10.1128/IAI.01750-05

Quote:

Originally Posted by Excargodog (Post 3294179)

The fitter virus is the new one, i can't even call it what they do because it is so retarded this nomenclature used...

Regardless, it is the fitter of the others, that is why it became dominant. Its dominance is conferred from the jabs. That is what they are inferring here.

2009. Director of NIAID Anthony Fauci proclaims children must have 2 jabs of the H1N1.

What happened to the 2009 H1N1 pandemic? Oh yeah, it got rat holed. You know, because the obama declared it over in july.

But this is new and novel. Yeah right.

Same play book, just now they have more compliant idiots to suck down their koolaid.

https://www.webmd.com/cold-and-flu/n...wine-flu-shots