You will get hired with the minimums and a pulse but training is a different story. Start digging into the regulations and any training manuals you can get a hold of (CRJ, ERJ, cargo ops planes, etc). Everything Explained is a great start. Make sure you are a proficient IFR pilot, not a proficient computer flyer. SIMs are amazing at practicing unique/far away approaches, flying faster than you are used to approaches, and possibly doing a CRJ simulator course at a nearby university/major flight school.

If you make it through training at a place like a 135 cargo op. You might be flying solo, at night, in a snowstorm, with steam gauges, in a turbo prop you have only a few hours in, and no one but ATC to hold your hand.

Don't cheat your way through experience. Buying/renting your way to a job is totally fine if you challenge yourself and always maintain proficiency. Getting a CFI should do that for you automatically unless you are one of those instructors that is in it just to get hours and get out. That is a complete disservice to students but unfortunately those instructors are in demand because of their CFI license in their pocket.

Fly safe and don't let complacency get the best of you!

 

I had a MEI student once who had a house three states North and had 1400+ hrs flying his own Seneca back and forth. He also flew a lot for his business.
That's a different story to time building on your own.
I'd recommend against the majority of your time being solo time building time.
At least join the Civil Air Patrol or offer your time to Angel Flight.