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GeeWizDriver 03-23-2021 05:08 AM

Many have posted their experiences with receiving the vaccine and relating that their INJECTION side effects have been minimal to moderate and therefore some opine that any concerns about side effects are unwarranted. That ignores an important reality. Many of those reluctant to take the needle are concerned about the LONGER TERM side effects that may still surface. Especially for women of child-bearing age.

The risk-reward analysis of protection from Covid versus potential long term negative side effects of the vaccine for 75 year old grumpy Grandpa is completely different for 35 year old Susie Homemaker. Some thought thalidomide was wonderful for a little while too.

Many states still haven't even gotten to a point where the priority system has given way to a come one, come all system so I think the vaccine shaming that is already starting is more than a little premature.

highfarfast 03-23-2021 05:10 AM

Quote:

Originally Posted by GeeWizDriver (Post 3210495)
Many have posted their experiences with receiving the vaccine and relating that their INJECTION side effects have been minimal to moderate and therefore some opine that any concerns about side effects are unwarranted. That ignores an important reality. Many of those reluctant to take the needle are concerned about the LONGER TERM side effects that may still surface. Especially for women of child-bearing age.

The risk-reward analysis of protection from Covid versus potential long term negative side effects of the vaccine for 75 year old grumpy Grandpa is completely different for 35 year old Susie Homemaker. Some thought thalidomide was wonderful for a little while too.

Many states still haven't even gotten to a point where the priority system has given way to a come one, come all system so I think the vaccine shaming that is already starting is more than a little premature.

What are the potential longer term side effects?

rickair7777 03-23-2021 06:18 AM

Quote:

Originally Posted by Mesabah (Post 3210453)
Yes, but engineered modRNA is not real mRNA, thus you get an antibody that is slightly different than the natural infection. They work based on cross reactivity in neutralizing the spike protein. That's why Pfizer/Moderna are setting up long term booster dosages going forward to keep vaccine induced antibody levels high. Your body will NOT produce additional antibodies in the future when it is exposed to Covid19, or a future variant, like they would with natural infection/other vaccines.

Actually the data I've seen hints at vaccine-induced memory cells which will react to a future infection. That's the where the long-term immunity (to any bug) comes from. Need more time either way to observe how it holds up in the real world. But it's common for vaccine-induced immunity to be better than natural immunity, and its' guaranteed to be more consistent across the population.

Quote:

Originally Posted by Mesabah (Post 3210453)
Also, from the investor conferences, Pfizer plans to launch an influenza mRNA vaccine later in the year. I assume they will also have one for the Zika virus soon as well.

Yes. Silver lining to covid is probably going top be a whole new class of mRNA vaccines, and hopefully some therapeutics as well, now that covid forced it center stage.

https://www.reuters.com/article/us-h...-idUSKBN2BF13R

GeeWizDriver 03-23-2021 06:21 AM

Quote:

Originally Posted by highfarfast (Post 3210497)
What are the potential longer term side effects?

That’s the point. We don’t know. Perhaps none. Likely none. But some are proceeding cautiously and that is their right, especially if they are in a low risk category.

Zard 03-23-2021 06:24 AM

Quote:

Originally Posted by BoilerUP (Post 3210482)
Many of the same kind of people who say "Stop being afraid of a virus with a 99.5% chance of survival" appear to have the mindset of "We should be concerned about a vaccine that 99.999% doesn't have significant side effects".

I'm 100% in the "you do you" camp, but do find it funny how humans of all ideological persuasions struggle with risk assessment when it involves their own biases and fears...

Got my first dose of Pfizer yesterday - nothing worse than a sore arm, though I do have 120Mbps download speeds and for some reason woke up hearing the Windows startup sound.


Are you able to answer your phone without picking it up now?

TransWorld 03-23-2021 06:36 AM

Quote:

Originally Posted by highfarfast (Post 3210497)
What are the potential longer term side effects?

Growing that third eye, like I’ve been talking about.

skywatch 03-23-2021 07:38 AM

Quote:

Originally Posted by BoilerUP (Post 3210482)
Many of the same kind of people who say "Stop being afraid of a virus with a 99.5% chance of survival" appear to have the mindset of "We should be concerned about a vaccine that 99.999% doesn't have significant side effects"..

I think it does make some sense, just not taken to an extreme. I think the point is, if I don't need the vaccine, why take it? Even if there is a very small chance (and there likely is, but your 99.999% statistic is of course made up - they just have not studied enough to know what the long term side effects could be) of some kind of harm, why take on that small chance to get a vaccination you don't need? Would you feel different if you wind up some day with Guillain-Barré syndrome, tracked back to a vaccination you really did not need?

To be clear - my thing is not anti-vax. Very much pro-vax. My parents are vaccinated - I support that 100% for people at risk. But for some people (and there are lots of them) that are not at particularly high risk, does it make sense given what we know at this point (very little about long term impacts) to be pushing this on otherwise completely healthy, very low risk people?

rickair7777 03-23-2021 09:52 AM

Quote:

Originally Posted by skywatch (Post 3210544)
I think it does make some sense, just not taken to an extreme. I think the point is, if I don't need the vaccine, why take it? Even if there is a very small chance (and there likely is, but your 99.999% statistic is of course made up - they just have not studied enough to know what the long term side effects could be) of some kind of harm, why take on that small chance to get a vaccination you don't need? Would you feel different if you wind up some day with Guillain-Barré syndrome, tracked back to a vaccination you really did not need?

To be clear - my thing is not anti-vax. Very much pro-vax. My parents are vaccinated - I support that 100% for people at risk. But for some people (and there are lots of them) that are not at particularly high risk, does it make sense given what we know at this point (very little about long term impacts) to be pushing this on otherwise completely healthy, very low risk people?

The way it's looking right now, the vaccines approved in the US are safer than getting covid for pretty much anyone over about 20. Time will tell, but it might well be safer for them too.

Plus the hassle of getting sick and quarantined for weeks.

LAXtoDEN 03-23-2021 09:58 AM

Quote:

Originally Posted by rickair7777 (Post 3210586)
The way it's looking right now, the vaccines approved in the US are safer than getting covid for pretty much anyone over about 20. Time will tell, but it might well be safer for them too.

Plus the hassle of getting sick and quarantined for weeks.

My dad got his last week and was sick as a dog for 3 days.

I’m too young (mid 20’s) to be considered a priority, but I’m just fine with that! I’ll let you guys test your medicals first.

Ronaldo 03-23-2021 10:01 AM

Quote:

Originally Posted by skywatch (Post 3210544)
I think it does make some sense, just not taken to an extreme. I think the point is, if I don't need the vaccine, why take it? Even if there is a very small chance (and there likely is, but your 99.999% statistic is of course made up - they just have not studied enough to know what the long term side effects could be) of some kind of harm, why take on that small chance to get a vaccination you don't need? Would you feel different if you wind up some day with Guillain-Barré syndrome, tracked back to a vaccination you really did not need?

To be clear - my thing is not anti-vax. Very much pro-vax. My parents are vaccinated - I support that 100% for people at risk. But for some people (and there are lots of them) that are not at particularly high risk, does it make sense given what we know at this point (very little about long term impacts) to be pushing this on otherwise completely healthy, very low risk people?

To clarify, weren’t you against lockdowns? Purportedly, to advance herd immunity. But now you are claiming that healthy people shouldn’t get the vaccine? That makes achieving herd immunity very difficult.

I’m sorry if I got you mixed up with someone else.


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