Pfizer granted regular FDA approval...

https://www.reuters.com/business/hea...ne-2021-08-23/

IR finds that booster shots reduce infection by a factor of four compared to two doses (5-6 times better against severe covid). They've only done boosters for 60+ so far...


https://www.reuters.com/world/middle...sk-2021-08-22/

This data is specific to their demographic, which means people who got the first two doses very early in 2021. It also doesn't measure any drop-off from the third dose yet (obviously).

https://i.ibb.co/WPj62z7/82769812-6-...4-C112-CA3.jpg

https://finance.yahoo.com/news/india...085900052.html

Stolen from United thread…..

https://www.fda.gov/media/150386/download

I'd have to do some research to really form an opinion but I suspect that a DNA vaccine might be the one technology which might actually need a longer-term trial.

J&J booster study show a x9 increase in antibodies, compared to one month after the original dose. This will likely lead to the fed recommending J&J boosters.

Article on WSJ (paywall).

UK study shows mRNA efficacy declines within six months, more indication that boosters are useful. Declining antibody levels was previously reported by the mfgs.

https://www.reuters.com/business/hea...rs-2021-08-25/

Remember those UK studies from months ago showing that an 8-12 week gap between Pfizer doses led to significantly higher antibodies than the 3 week interval?

This is sort of interesting…
 

https://thehill.com/policy/healthcar...fizer-research

It looks like at least a portion of the duration of effectiveness of the Moderna and Pfizer vaccines is because immunization is particularly effective in those who have already had COVID, giving higher antibody levels than in COVID naive individuals. Now that’s not really surprising, but it does make you wonder to what extent the benefit being touted by vaccination comes from people who already had antibodies aboard before being immunized and weren’t all that high risk to begin with.

Remember the trials? Double blind with control groups?

The controls accounted for any *effective* existing natural immunity, whether it was genetic, acquired from a previous coronavirus, or from covid-19.

The vaccines provided near-perfect protection against severe covid COMPARED TO THE CONTROLS. Plausible that some of that benefit was due to existing natural immunity + vaccine, but obviously existing natural immunity alone was not enough to get the death rate low enough for society in general to be cool with it.