Vaccine Development Summary
11-12-2021, 06:37 AM
#1061
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,293
Originally Posted by Mesabah
People with a BMI over 30 don't appear to be able to produce neutralizing antibodies to the spike.
11-12-2021, 06:06 PM
#1062
Gets Weekends Off
Joined APC: Mar 2011
Position: Left seat on a kite
Posts: 1,884
Originally Posted by rickair7777
Link? Is this from one of the vaccines, covid infection, or both?
I think that he is pointing to the fact that people with a BMI greater than 25 but less than 30 who have been infected with the actual virus are on that graph. Vaccine isn't Covid.
11-13-2021, 06:43 AM
#1063
Gets Weekends Off
Joined APC: Jan 2016
Posts: 417
A quick search on Google found it -
The majority of SARS-CoV-2-specific antibodies in COVID-19 patients with obesity are autoimmune and not neutralizing
Interesting read - but my background is software and electronics, so I'm pretty far out of my element on this.
The majority of SARS-CoV-2-specific antibodies in COVID-19 patients with obesity are autoimmune and not neutralizing
Interesting read - but my background is software and electronics, so I'm pretty far out of my element on this.
11-13-2021, 06:46 AM
#1064
Gets Weekends Off
Joined APC: Nov 2020
Position: Enoch Powell Enthusiast
Posts: 2,124
Originally Posted by bradthepilot
A quick search on Google found it -
The majority of SARS-CoV-2-specific antibodies in COVID-19 patients with obesity are autoimmune and not neutralizing
Interesting read - but my background is software and electronics, so I'm pretty far out of my element on this.
The majority of SARS-CoV-2-specific antibodies in COVID-19 patients with obesity are autoimmune and not neutralizing
Interesting read - but my background is software and electronics, so I'm pretty far out of my element on this.
11-14-2021, 09:08 AM
#1065
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,293
Originally Posted by RI830
It says in the graph....."COVID" or "NO COVID".
I think that he is pointing to the fact that people with a BMI greater than 25 but less than 30 who have been infected with the actual virus are on that graph. Vaccine isn't Covid.
I think that he is pointing to the fact that people with a BMI greater than 25 but less than 30 who have been infected with the actual virus are on that graph. Vaccine isn't Covid.
11-14-2021, 06:02 PM
#1066
Gets Weekends Off
Joined APC: Jan 2016
Posts: 417
Originally Posted by rickair7777
Taking a graph out like that out of context with the associated write-up is likely to be misleading... in this case the graph title is not even shown.
11-16-2021, 06:45 AM
#1067
:-)
Joined APC: Feb 2007
Posts: 7,339
Originally Posted by bradthepilot
I completely agree, which is why I took some time and found the study the graph was pulled from and linked it in my previous post. I put it up here in the hopes that someone smarter than me about these things (maybe you or someone else) might share some thoughts and I could see how close my understanding of the study and results is to yours...
11-17-2021, 04:07 PM
#1068
Speed, Power, Accuracy
Joined APC: Sep 2007
Position: PIC
Posts: 1,702
A new in-vitro study that indicates the spike proteins, whether from the bug OR the injections, impede DNA repair. Discussion section suggests a move away from full spike protein vaccines.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538446/
Money quote:
In contrast, our data provide valuable details on the involvement of spike protein subunits in DNA damage repair, indicating that full–length spike–based vaccines may inhibit the recombination of V(D)J in B cells, which is also consistent with a recent study that a full–length spike–based vaccine induced lower antibody titers compared to the RBD–based vaccine [28]. This suggests that the use of antigenic epitopes of the spike as a SARS–CoV–2 vaccine might be safer and more efficacious than the full–length spike.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538446/
Money quote:
In contrast, our data provide valuable details on the involvement of spike protein subunits in DNA damage repair, indicating that full–length spike–based vaccines may inhibit the recombination of V(D)J in B cells, which is also consistent with a recent study that a full–length spike–based vaccine induced lower antibody titers compared to the RBD–based vaccine [28]. This suggests that the use of antigenic epitopes of the spike as a SARS–CoV–2 vaccine might be safer and more efficacious than the full–length spike.
11-19-2021, 08:44 AM
#1069
Prime Minister/Moderator
Joined APC: Jan 2006
Position: Engines Turn Or People Swim
Posts: 39,293
FDA approves Pfizer and Moderna boosters for all adults...
https://www.foxbusiness.com/lifestyl...sters-approved
https://www.foxbusiness.com/lifestyl...sters-approved
11-19-2021, 10:01 AM
#1070
Gets Weekends Off
Joined APC: Nov 2020
Position: Enoch Powell Enthusiast
Posts: 2,124
Originally Posted by rickair7777
FDA approves Pfizer and Moderna boosters for all adults...
https://www.foxbusiness.com/lifestyl...sters-approved
https://www.foxbusiness.com/lifestyl...sters-approved
Which, to be fair, the posted article states.
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