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Hydroxychloroquine increases Covid survival


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Hydroxychloroquine increases Covid survival

Old 07-03-2020 | 03:20 PM
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Originally Posted by DC8DRIVER
For the original poster who may be in favor of stirring the pot or simply adverse to doing any research or fact finding, below is a very recent article that referrs to an actual study of facts that reveals an (almost) one-in-ten chance of death in their study group. Of those who survived, a significant number had cardiac toxicity issues resulting in arrhythmia, tachycardia, or fibrillation problems ... so good luck with that EKG during your next medical. Of course, if he is young enough to not need the EKG, I'm sure the answer will be "tough beans you old (senior) farts!"

https://www.accessdata.fda.gov/drugs...0_Redacted.pdf

https://www.fda.gov/drugs/drug-safet...tal-setting-or
Take that up with Henry Ford Health System for doing the study, and with CNN for publishing the results.

I only post the news, pal.
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Old 07-03-2020 | 05:13 PM
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Originally Posted by DC8DRIVER
For the original poster who may be in favor of stirring the pot or simply adverse to doing any research or fact finding, below is a very recent article that referrs to an actual study of facts that reveals an (almost) one-in-ten chance of death in their study group. Of those who survived, a significant number had cardiac toxicity issues resulting in arrhythmia, tachycardia, or fibrillation problems ... so good luck with that EKG during your next medical. Of course, if he is young enough to not need the EKG, I'm sure the answer will be "tough beans you old (senior) farts!"

https://www.accessdata.fda.gov/drugs...0_Redacted.pdf

https://www.fda.gov/drugs/drug-safet...tal-setting-or
Yeah... the drug is super unsafe. It’s only been around for nearly 5 decades and millions of people use it globally every day...
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Old 07-03-2020 | 06:00 PM
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Originally Posted by DC8DRIVER
For the original poster who may be in favor of stirring the pot or simply adverse to doing any research or fact finding, below is a very recent article that referrs to an actual study of facts that reveals an (almost) one-in-ten chance of death in their study group. Of those who survived, a significant number had cardiac toxicity issues resulting in arrhythmia, tachycardia, or fibrillation problems ... so good luck with that EKG during your next medical. Of course, if he is young enough to not need the EKG, I'm sure the answer will be "tough beans you old (senior) farts!"

https://www.accessdata.fda.gov/drugs...0_Redacted.pdf

https://www.fda.gov/drugs/drug-safet...tal-setting-or
EVERY "official" study EXCEEDED the known daily dosage limit of 200mg per day as part of the study protocol. They were giving people THREE TIMES the limit because of 65 years of data about proper therapeutic dose versus toxic dose. And I'm still waiting for an "official" study that combines the PROPER dosage of HCQ with ZINC and Z Pac. It isn't the HCQ that provides the benefit. It's the ZINC but it needs the HCQ to "unlock" the cell to allow the zinc inside and interrupt reproduction of the virus.

If you don't think there has been a concerted, financially and politically motivated effort to discredit HCQ therapy, you probably think Epstein killed himself, too.
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Old 07-03-2020 | 07:46 PM
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Originally Posted by GeeWizDriver
EVERY "official" study EXCEEDED the known daily dosage limit of 200mg per day as part of the study protocol. They were giving people THREE TIMES the limit because of 65 years of data about proper therapeutic dose versus toxic dose. And I'm still waiting for an "official" study that combines the PROPER dosage of HCQ with ZINC and Z Pac. It isn't the HCQ that provides the benefit. It's the ZINC but it needs the HCQ to "unlock" the cell to allow the zinc inside and interrupt reproduction of the virus.

If you don't think there has been a concerted, financially and politically motivated effort to discredit HCQ therapy, you probably think Epstein killed himself, too.

So they refuse to use a treatment that works because of it not making a profit but then show a far cheaper drug to work? HCQ has failed in like 6 countries. Also you are aware that the studies it has failed are double blind which prevents that kind of data tampering. The data is then reviewed by a data review board that monitors for incorrect data. Sorry HCQ has failed. Dexo and remedesvir have at least proven to work during double blind studies. Science giving us answers just not always the ones we want.
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Old 07-03-2020 | 07:52 PM
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Originally Posted by Downtime
So they refuse to use a treatment that works because of it not making a profit but then show a far cheaper drug to work? HCQ has failed in like 6 countries. Also you are aware that the studies it has failed are double blind which prevents that kind of data tampering. The data is then reviewed by a data review board that monitors for incorrect data. Sorry HCQ has failed. Dexo and remedesvir have at least proven to work during double blind studies. Science giving us answers just not always the ones we want.
Those studies "failed" because they OVERDOSED the subjects which induced negative cardiac resuls and/or didn't include zinc in the protocol along with the HCQ. The STUDIES are flawed. Because they WANT them to fail.
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Old 07-03-2020 | 07:59 PM
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Originally Posted by Downtime
So they refuse to use a treatment that works because of it not making a profit but then show a far cheaper drug to work? HCQ has failed in like 6 countries. Also you are aware that the studies it has failed are double blind which prevents that kind of data tampering. The data is then reviewed by a data review board that monitors for incorrect data. Sorry HCQ has failed. Dexo and remedesvir have at least proven to work during double blind studies. Science giving us answers just not always the ones we want.
There's a tendency to over simplify covid treatments, thinking that there's a single therapy or drug that will be a magic cure-all. The reality of covid is more complex, and covid appears to have multiple stages that require different approaches in each stage. The late stages are by far the most troublesome, and it may be that we are never able to effectively treat late stage covid very effectively (the goal would be to avoid progressing to this stage). I don't think anybody is saying that HCQ is the wonder drug that cures covid in all forms, but it keeps coming up as something that appears to help (depending on the stage and circumstances).

Dismissing HCQ as worthless seems questionable at this point. It may be useful as a preventive measure in high-risk groups or in the early stages of the disease. On the contrary, it's not unreasonable to conclude that there seems to be a purposeful effort in some quarters to discredit HCQ for political reasons.
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Old 07-03-2020 | 09:53 PM
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Originally Posted by DC8DRIVER
For the original poster who may be in favor of stirring the pot or simply adverse to doing any research or fact finding, below is a very recent article that referrs to an actual study of facts that reveals an (almost) one-in-ten chance of death in their study group. Of those who survived, a significant number had cardiac toxicity issues resulting in arrhythmia, tachycardia, or fibrillation problems ... so good luck with that EKG during your next medical. Of course, if he is young enough to not need the EKG, I'm sure the answer will be "tough beans you old (senior) farts!"

https://www.accessdata.fda.gov/drugs...0_Redacted.pdf

https://www.fda.gov/drugs/drug-safet...tal-setting-or

Here is the peer reviewed article in the international journal of infectious diseases.

https://www.ijidonline.com/article/S...534-8/fulltext


And obviously some of the findings are contradictory and no doubt additional studies are even now underway to resolve that, but as far as cardiac toxicity of hydroxychloroquine and chloroquine, people should understand that until the rise of chloroquine resistant malaria, these drugs were mainstays of the WHO malaria control program and routinely taken by 100s of millions of people in malaria us areas for decades. While cardiac toxicity can and does occur, it did not occur with such frequency as to contraindicated its routine use in these areas.

https://www.ncbi.nlm.nih.gov/books/NBK2616/

https://pubmed.ncbi.nlm.nih.gov/29858838/

These drugs are still routinely used for medical indications far less threatening than being hospitalized In an ICU for COVID 19.

Whether they actually ARE effective will probably require further testing to confirm or refute, but both Aralen (chloroquine) and Plaquenil (hydroxy chloroquine) are FDA approved drugs widely prescribed for rheumatoid arthritis and antimalarial treatment worldwide.
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Old 07-04-2020 | 05:05 AM
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Originally Posted by Excargodog
Here is the peer reviewed article in the international journal of infectious diseases.

https://www.ijidonline.com/article/S...534-8/fulltext


And obviously some of the findings are contradictory and no doubt additional studies are even now underway to resolve that, but as far as cardiac toxicity of hydroxychloroquine and chloroquine, people should understand that until the rise of chloroquine resistant malaria, these drugs were mainstays of the WHO malaria control program and routinely taken by 100s of millions of people in malaria us areas for decades. While cardiac toxicity can and does occur, it did not occur with such frequency as to contraindicated its routine use in these areas.

https://www.ncbi.nlm.nih.gov/books/NBK2616/

https://pubmed.ncbi.nlm.nih.gov/29858838/

These drugs are still routinely used for medical indications far less threatening than being hospitalized In an ICU for COVID 19.

Whether they actually ARE effective will probably require further testing to confirm or refute, but both Aralen (chloroquine) and Plaquenil (hydroxy chloroquine) are FDA approved drugs widely prescribed for rheumatoid arthritis and antimalarial treatment worldwide.

Sure and most of those studies have been finished. This study was observational and thus does not have a double blind control group. It makes the study interesting but stacked up against double blind studies doesn’t pull much weight. I would find its politics suspect even if the trails were held in the US. That said it failed in six countries for hospitalized patients so it is ok to move on. Multiple drugs have failed in this setting. It’s ok they weren’t designed for it.
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Old 07-04-2020 | 05:55 AM
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Originally Posted by Anson Harris
There's a tendency to over simplify covid treatments, thinking that there's a single therapy or drug that will be a magic cure-all. The reality of covid is more complex, and covid appears to have multiple stages that require different approaches in each stage. The late stages are by far the most troublesome, and it may be that we are never able to effectively treat late stage covid very effectively (the goal would be to avoid progressing to this stage). I don't think anybody is saying that HCQ is the wonder drug that cures covid in all forms, but it keeps coming up as something that appears to help (depending on the stage and circumstances).

Dismissing HCQ as worthless seems questionable at this point. It may be useful as a preventive measure in high-risk groups or in the early stages of the disease. On the contrary, it's not unreasonable to conclude that there seems to be a purposeful effort in some quarters to discredit HCQ for political reasons.
Not only do the studies omit zinc and use too much HCQ, they are performed on hospitalized patients. The HCQ, z-pack, zinc cocktail is best used at the first onset of symptoms to slow replication. Giving it to someone 5 minutes before putting her on a ventilator then claiming it didn't work borders on fraud.
If it slows replication reliably it might also be useful as a prophylactic for people with possible exposure. That would be extremely useful for getting things back to normal.
But it sure wouldn't be as profitable as some patented concoction that could be sold for extortionate prices.
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Old 07-04-2020 | 06:04 AM
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Originally Posted by tallpilot
Not only do the studies omit zinc and use too much HCQ, they are performed on hospitalized patients. The HCQ, z-pack, zinc cocktail is best used at the first onset of symptoms to slow replication. Giving it to someone 5 minutes before putting her on a ventilator then claiming it didn't work borders on fraud.
If it slows replication reliably it might also be useful as a prophylactic for people with possible exposure. That would be extremely useful for getting things back to normal.
But it sure wouldn't be as profitable as some patented concoction that could be sold for extortionate prices.

You do realize every drug has been evaluated on vent patients right? So it’s not fraud it was the design of the study. Dexo was given to people on vents and cut deaths by a third. Sure it may have some value at some point but for now it has failed. So find me a double blind study that says it has any benefit early. Preferably with thousands of patients and robust control group. Studies or it did not happen.
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